12. November 2015

    Factors influencing the erosion rate and the drug release kinetics from organogels designed as matrices for oral controlled release of a hydrophobic drug

    This article proposes solid-like systems from sunflower oil structured with a fibrillar network built by the assembly of 12-hydroxystearic acid (12-HSA), a gelator molecule for an oil phase. The resulting organogels were studied as oral controlled release formulations for a lipophilic drug, Efavirenz (EFV), dissolved in the oil. 

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    Tags: excipient, Dosage, form, drug, delivery, process, release, formulation, lipid, Oral, Multiparticulate, Poorly, drugs, soluble, profile, models, Prilling, nov2015, Efavirenz, organogel