Process analytical technology, based on monitoring particle size distribution and tracking coating thickness measurements in real time, can be used to predict the dissolution of polymer-coated multiparticulates.
Process analytical technology, based on monitoring particle size distribution and tracking coating thickness measurements in real time, can be used to predict the dissolution of polymer-coated multiparticulates.Process analytical technology (PAT) describes the use of analytical instruments to measure specific product attributes during manufacturing, substantially minimizing the need to sample product for off-line analysis. This approach offers several key advantages including the ability to take process measurements in situ, with instant access to data, facilitating rapid decision making during product development and manufacturing.
By Piyush Patel, Edward Godek, Chris O’Callaghan, Ian Jones
Pharmaceutical Technology
Volume 2017 Supplement, Issue 2, pg s20-s25
