Solid lipid microparticles: an approach for improving oral bioavailability of aspirin
The objectives of the work were to develop a lipid based delivery system for aspirin and to evaluate its physicochemical and the pharmacodynamic properties. Aspirin-loaded solid lipid microparticles (SLMs) were formulated by hot homogenization and analysed for their encapsulation efficiency (EE%), in vitro release, particle size, anti-inflammatory and ulcer inhibition properties