Effect of increasing microcrystalline cellulose concentration on the fl ow properties of DC diluents
DFE Pharma
R. Shegokar1, E. Stone2 and J. Langridge1
1DFE Pharma, Kleverstr. 187, Goch, Germany and 2Merlin Powder Characterisation Ltd, Loughborough, UK.
R. Shegokar1, E. Stone2 and J. Langridge1
1DFE Pharma, Kleverstr. 187, Goch, Germany and 2Merlin Powder Characterisation Ltd, Loughborough, UK.
Comparing Drug Layering and Direct Pelletization Processes
The extended-release performance of drug-loaded pellets manufactured by two methods, drug layering and direct pelletization, was compared.
Mar 02, 2014 by Ed Godek [1] - Pharmaceutical Technology
http://www.pharmtech.com/comparing-drug-layering-and-direct-pelletization-processes
Mar 02, 2014 by Ed Godek [1] - Pharmaceutical Technology
http://www.pharmtech.com/comparing-drug-layering-and-direct-pelletization-processes
FORMULATION DEVELOPMENT OF MOUTH DISSOLVING FILM OF ETORICOXIB FOR PAIN MANAGEMENT
Etoricoxib is a potent, orally active, highly selective COX-2 inhibitor that exhibits anti-inflammatory, analgesic, and antipyretic activities. The present research was undertaken to develop Mouth Dissolving Films of Etoricoxib to have rapid onset of action.
Omyapharm FCC
A new generation of multifunctional mineral excipient
- Innovative functionalized excipient for pharmaceuticals
- High efficiency carrier for multiple substances
- Controlled-release properties
- Innovative functionalized excipient for pharmaceuticals
- High efficiency carrier for multiple substances
- Controlled-release properties
Making better Tablets: A QbD Approach
Michael Gamlen - Gamlen Tableting
Joe Dominque - SciMark International
Orginal Source: http://www.tabletscapsules.com/
Joe Dominque - SciMark International
Orginal Source: http://www.tabletscapsules.com/
Platform Formulation Development Using a Novel Pulmonary Excipient and In Vivo Evaluation of a Model Formulation of Fluticasone Propionate
David T. Vodak1, Dwayne Friesen1, Dan E. Dobry1, Philip J. Kuehl2, Melanie Doyle-Eisele2, Jacob D. McDonald2, Warren K. Miller1, and David K. Lyon1
(1. Bend Research Inc., 64550 Research Rd., Bend, Oregon 97701 U.S.A.▪541-382-4100▪www.bendres.com; 2. Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr. S.E., Albuquerque, New Mexico 87108 U.S.A.▪www.lrri.org▪505-348-9400)
(1. Bend Research Inc., 64550 Research Rd., Bend, Oregon 97701 U.S.A.▪541-382-4100▪www.bendres.com; 2. Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr. S.E., Albuquerque, New Mexico 87108 U.S.A.▪www.lrri.org▪505-348-9400)
An Analysis of Carrier/API Association: Morphologically Directed Raman Microscopy to Characterize a Dry Powder Inhaler
Linda H. Kidder, Kenneth S. Haber, Janie Dubois, and E. Neil Lewis
Malvern Instruments • 7221 Lee Deforest Drive • Suite 300 • Columbia, MD 21046
Malvern Instruments • 7221 Lee Deforest Drive • Suite 300 • Columbia, MD 21046
Integration of Risk Management into existing pharmaceutical Quality Systems
http://de.scribd.com/doc/236204752/34/Risk-based-raw-material-supplier-qualification
Formulation and Evaluation of Bilayer Tablets of Glimepiride and Metformin HCL
Pamu. Sandhya1, 2, Faheem Unnisa Begum1, Afreen1
1Department of Pharmaceutics, Shadan Womens College of Pharmacy, 500 004, Hyderabad, India 2University College of Technology, Osmania University, Hyderabad, 500 007, India
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
e-ISSN: 2278-3008, p-ISSN:2319-7676. Volume 9, Issue 1 Ver. IV (Jan. 2014), PP 38-45
www.iosrjournals.org
1Department of Pharmaceutics, Shadan Womens College of Pharmacy, 500 004, Hyderabad, India 2University College of Technology, Osmania University, Hyderabad, 500 007, India
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
e-ISSN: 2278-3008, p-ISSN:2319-7676. Volume 9, Issue 1 Ver. IV (Jan. 2014), PP 38-45
www.iosrjournals.org
Optimization Direct Compression’s Co - Processed Excipient Microcrystalline Cellulose PH 102 and Povidone ® K 30
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) vol.9 issue.2 version.4
Evidence-Based Nanoscopic and Molecular Framework for Excipient Functionality in Compressed Orally Disintegrating Tablets
Ali Al-khattawi1,3, Hamad Alyami1, Bill Townsend2,3, Xianghong Ma2,3, Afzal R. Mohammed1,3*
1 Aston School of Pharmacy, Aston University, Birmingham, United Kingdom, 2 School of Engineering and Applied Science, Aston University, Birmingham, United
Kingdom, 3 Aston Research Centre for Healthy Ageing, Aston University, Birmingham, United Kingdom
1 Aston School of Pharmacy, Aston University, Birmingham, United Kingdom, 2 School of Engineering and Applied Science, Aston University, Birmingham, United
Kingdom, 3 Aston Research Centre for Healthy Ageing, Aston University, Birmingham, United Kingdom
Biopolymers in Drug Delivery: Recent Advances and Challenges, 7-26 7 African Tropical Plant Gums: Grossly Unexploited Carriers or Adjuncts in Drug Delivery Systemsmore
Vincent C. Okore
Department of Pharmaceutics, University of Nigeria, Nsukka, Nigeria
Biopolymers in Drug Delivery: Recent Advances and Challenges, 7-26
Department of Pharmaceutics, University of Nigeria, Nsukka, Nigeria
Biopolymers in Drug Delivery: Recent Advances and Challenges, 7-26
Original download Academaia.edu:
EXPLORATION OF NOVEL CO-PROCESSED MULTIFUNCTIONAL EXCIPIENT FOR TABLET DOSAGE FORM
Digesh D. Shah, Rajnikant M. Suthar*, Ajay B. Sola
The aim of the present investigation is to formulate novel co-processed multifunctional excipient for tablet dosage form. Co- processed particles of chitosan, microcrystalline cellulose (MCC) and aerosil-200 were fabricated by wet granulation technique to be used as a directly compressible excipient in tablet formulation. The developed co-processed excipients (CPE) were evaluated for their excipient related and dosage form related parameters. As expected, all the prepared batches exhibited acceptable angle of repose (<350) and quick disintegration time (<1min). The intimate physical association between chitosan, MCC and aerosil-200 has created an insoluble, hydrophilic, highly absorbent material, resulting in superiority in water uptake, water saturation for gelling formation, and compactability among other superdisintegrants. The developed CPE could be act as a superdisintegrant and pharmaceutical filler at the same time.
The aim of the present investigation is to formulate novel co-processed multifunctional excipient for tablet dosage form. Co- processed particles of chitosan, microcrystalline cellulose (MCC) and aerosil-200 were fabricated by wet granulation technique to be used as a directly compressible excipient in tablet formulation. The developed co-processed excipients (CPE) were evaluated for their excipient related and dosage form related parameters. As expected, all the prepared batches exhibited acceptable angle of repose (<350) and quick disintegration time (<1min). The intimate physical association between chitosan, MCC and aerosil-200 has created an insoluble, hydrophilic, highly absorbent material, resulting in superiority in water uptake, water saturation for gelling formation, and compactability among other superdisintegrants. The developed CPE could be act as a superdisintegrant and pharmaceutical filler at the same time.
Formulation of inhalable lipid-based salbutamol sulfate microparticles by spray drying technique
DARU Journal of Pharmaceutical Sciences 2014, 22:50 doi:10.1186/2008-2231-22-50
Zahra Daman (z_daman@yahoo.com)
Kambiz Gilani (gilani@tums.ac.ir)
Abdolhossein Rouholamini Najafabadi (roholami@tums.ac.ir)
Hamid Reza Eftekhari (hre62@yahoo.fr)
Mohammad Ali Barghi (barghi.ali@khayam.ut.ac.ir)
Zahra Daman (z_daman@yahoo.com)
Kambiz Gilani (gilani@tums.ac.ir)
Abdolhossein Rouholamini Najafabadi (roholami@tums.ac.ir)
Hamid Reza Eftekhari (hre62@yahoo.fr)
Mohammad Ali Barghi (barghi.ali@khayam.ut.ac.ir)
Tamarind Seed Polysaccharide and its Modifications- Versatile Pharmaceutical Excipients – A Review
Rashmi Manchanda*, S.C. Arora, Rajesh Manchanda
RKSD College of Pharmacy, Kaithal – 136027, Haryana, India.
*Corres.Author: rashmipharma23@yahoo.in
RKSD College of Pharmacy, Kaithal – 136027, Haryana, India.
*Corres.Author: rashmipharma23@yahoo.in
An Improved 2-Step Process for Moisture Sensitive Drugs Using Syloid® FP Silicas
Grace materials technology
www.SyloidFP.com
www.SyloidFP.com
Optimization Direct Compression’s Co-Processed Excipient Microcrystalline Cellulose PH 102 and Povidone® K 30
*Aris Perdana Kusuma1,2, Achmad Fudholi2, Akhmad Kharis Nugroho2
1(Dept. of Pharmacy, Islamic University of Indonesia, Yogyakarta, Indonesia)
2(Pharmacy Faculty, Gadjah Mada University, Yogyakarta, Indonesia)
1(Dept. of Pharmacy, Islamic University of Indonesia, Yogyakarta, Indonesia)
2(Pharmacy Faculty, Gadjah Mada University, Yogyakarta, Indonesia)
INNOVATIVE FUID BED TECHNOLOGIES FOR TASTE-MASKED MICROPELLETS DESIGN
M. Guhmann, F. Gerber, A. Grave, N. Poellinger
Glatt Pharmaceutical Services, 79589 Binzen, Germany
Glatt Pharmaceutical Services, 79589 Binzen, Germany
Investigation of Novel Multifunctional Co-Processed Excipient for Direct Compression
S.M. Ambore, Jyoti Tekale and S.G. Gattani
School of Pharmacy, Swami Ramanand Teerth Marathawada University,
Vishnupuri -431606, Nanded, India
School of Pharmacy, Swami Ramanand Teerth Marathawada University,
Vishnupuri -431606, Nanded, India
COMPRESSION COATED TABLETS AS DRUG DELIVERY SYSTEM (TABLET IN TABLET ) : A REVIEW
Rohit Pawar1*,
Manish Jaimini1, Bhupendra S. Chauhan1, Sanjay K. Sharma1
1Department of pharmaceutics, Jaipur college of pharmacy, Jaipur.
Manish Jaimini1, Bhupendra S. Chauhan1, Sanjay K. Sharma1
1Department of pharmaceutics, Jaipur college of pharmacy, Jaipur.
Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins
Ali M1, EL-Massik MA1, Abdallah OY2 and Abdelkader H*3
1Department of Pharmaceutics, Faculty of Pharmacy, Pharos University, Alexandria, Egypt
2Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt
3Department of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia, Egypt
1Department of Pharmaceutics, Faculty of Pharmacy, Pharos University, Alexandria, Egypt
2Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt
3Department of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia, Egypt
Pharmaceutical excipients – an overview including considerations for paediatric dosing
Training workshop: Pharmaceutical development with focus on pediatric formulations
Presenter: Dr Simon Mills
Beijing, 21 to 25 June 2010
Presenter: Dr Simon Mills
Beijing, 21 to 25 June 2010
Film Coating for Pediatric Oral Solid Dosage Forms
Colorcon 2014
WP_ped_color__V1_0114
WP_ped_color__V1_0114
Ternary solid solutions, obtained by hot melt extrusion (hme) of itraconazole in a binary matrix
K.W. Chooi1,2, J. Fraser2, D.S. Jones1 and G.P. Andrews1
1School of Pharmacy, Queen’s University Belfast, Belfast, UK. 2Encap Drug Delivery, A division of Capsugel® Dosage Form Solutions, Livingston, UK.
1School of Pharmacy, Queen’s University Belfast, Belfast, UK. 2Encap Drug Delivery, A division of Capsugel® Dosage Form Solutions, Livingston, UK.
Excipient Selection In Parenteral Formulation Development
Sougata Pramanick*, Deepak Singodia, Vikas Chandel
R&D, Emcure Pharmaceuticals Limited, P1-2, Hinjwadi, Pune – 411057.
Keywords: Excipients, Parenterals, Lyophilized, Suspension, formulation development
R&D, Emcure Pharmaceuticals Limited, P1-2, Hinjwadi, Pune – 411057.
Keywords: Excipients, Parenterals, Lyophilized, Suspension, formulation development
Raising Expectations on Excipients
FRED MONSUUR, JULIA PONCHER - W.R. GRACE & Co.
Chimica oggi / Chemistry today - vol 28 n 5 - September/October 2010 - Focus on Excipients
Chimica oggi / Chemistry today - vol 28 n 5 - September/October 2010 - Focus on Excipients
Simultaneous Spherical Crystallization and Co-Formulation of Drug (s) and excipient from Microfluidic Double Emulsions
Reno AL Leon † , Wai Yew Wan † , Abu Zayed M. Badruddoza †, TA Hatton ‡ §, and Saif A. Khan * † ‡
Publication Date (Web): November 25, 2013
Copyright © 2013 American Chemical Society
Publication Date (Web): November 25, 2013
Copyright © 2013 American Chemical Society
Excipient Pedigree White Paper
At the request of FDA and with their input, IPEC-Americas and IPEC Europe have developed a position paper on the need and procedure for establishing the complete supply chain history of an excipient for use in pharmaceuticals, e.g., the excipient's "pedigree.
LIPID BASED DRUG DELIVERY SYSTEM: CLASSIFICATION, DRUG TRANSPORT ACROSS ENTEROCYTE, ROLE OF LIPID CHAIN LENGTH IN SUPPRESSION OF BODY FAT ACCUMULATION
Md. Habban Akhter1*, Govind Mohan1, Md. Hedaitullah2, Md. Khalid Iqbal2
1NIMS Institute of Pharmacy, NIMS University P.O. Box 303121, Jaipur, India.
2HIMT College of Pharmacy, Greater Noida (U.P), India.
Md. Habban Akhter et al. / International Journal of Pharmacy, 4(2), 2014, 98-108.
1NIMS Institute of Pharmacy, NIMS University P.O. Box 303121, Jaipur, India.
2HIMT College of Pharmacy, Greater Noida (U.P), India.
Md. Habban Akhter et al. / International Journal of Pharmacy, 4(2), 2014, 98-108.