02. March 2015
Mol. Pharmaceutics, 2015, 12 (3), pp 857–866 DOI: 10.1021/mp500692a Publication Date (Web): January 13, 2015 Copyright © 2015 American Chemical Society *E-mail:
[email protected] This study investigated the presence of specific drug–excipient interactions in amorphous solid dispersions of lapatinib (LB) and four commonly used pharmaceutical polymers, including Soluplus, polyvinylpyrrolidone vinyl acetate (PVPVA), hydroxypropylmethylcellulose acetate succinate (HPMCAS), and...