Calibration of the Drucker Prager Cap (DPC) model parameters provides a means for a deeper understanding of the impact of granule composition on the compaction properties of dry granules independent of their solid fraction. In this study, monodisperse granules of mixtures of microcrystalline cellulose and mannitol (0%, 25%, 50%, 75% and 100% mannitol) prepared as small cylindrical compacts with well-defined size, shape and solid fraction (0.58) were used as model dry granules. More
There is lot of confusion in the literatures regarding the method of production of nanoemulsion. According to some authors, only the methods using high energy like high-pressure microfluidizer or high-frequency ultra-sonic devices can produce actual nanoemulsions. In contrast to this concept, one research group reported for the first time the preparation of nanoemulsion by a low-energy method. Later on many authors reported about the low-energy emulsification method. More