09. May 2016

An ultrasound measurement system was employed as a non-destructive method to evaluate its reliability in predicting the tensile strength of tablets and investigate the ben- efits of incorporating it in a continuous line, manufacturing solid dosage forms. Tablets containing lactose, acetaminophen, and magnesium stearate were manufactured contin- uously and in batches. The effect of two processing parameters, compaction force and level of shear strain were examined. Young’s modulus and tensile...