Have existing pharmaceutical excipients failed to enable oral/nasal protein delivery?

ABSTRACT

It seems evident that the ill-defined weltanschauung of the past decade of enabling oral, un-truncated permeability-dependent protein delivery carte-blanche, using existing excipients has produced sparse results. Existing excipients are better utilized for exploiting niches which do not require either permeation or a permeation enhancement incongruent and/or is disproportionate to the existing excipient molecules' ability.

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