Orally disintegrating tablets (ODTs) are a preferred dosage form compared with conventional tablets because of the numerous advantages they offer, such as rapid dissolution and fast onset of action.
To maintain the porous structure needed for fast dispersion, most current ODT formulations are limited by their mechanical strength. With functionalised calcium carbonate, however, pharmaceutical manufacturers can produce ODTs that offer high mechanical strength while disintegrating twice as fast as comparable tablets.
ODTs are becoming increasingly important in the pharmaceutical market, both for prescription and over-the-counter medications, and can significantly enhance patient compliance. As they can be swallowed without the need for water, these dosage forms are particularly convenient for children and the elderly, and they’re the delivery format of choice for people who want to take their medicine ‘on the go.’ They are also particularly helpful for patients who have difficulty swallowing — a complication associated with a number of age-related conditions, including stroke and Parkinson’s disease.