Eye on Excipients: A new coprocessed ODT excipient

Developing orally disintegrating tablets (ODTs) is a worldwide trend, but it’s particularly popular in Japan, where formulators at innovator companies, generic drug companies, and contract manufacturers compete to develop new ODTs. In fact, Japan accounts for the largest share of ODTs

in the world [1]. Traditionally, manufacturing ODTs was a wet process that required special

manufacturing equipment. Lyophilization is one example. In recent years, however, new excipients and excipient blends have enabled manufacturers to produce ODTs using conventional equipment, i.e., blenders and tablet presses.

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