THIOMERS - A BLESSING TO EVOLUTING ERA OF PHARMACEUTICALS
Thiomers are the polymers modified for the mucoadhesive properties and other additive
properties by incorporating thiol moieties in the backbone of the unmodified polymeric chain by exchange reactions or simple oxidation reactions. Drug that are less soluble and permeable can be complexed with thiomers for their increased absorption through the mucosal membranes by increase in contact time and prolonged stay in body due to mucoadhesion.
properties by incorporating thiol moieties in the backbone of the unmodified polymeric chain by exchange reactions or simple oxidation reactions. Drug that are less soluble and permeable can be complexed with thiomers for their increased absorption through the mucosal membranes by increase in contact time and prolonged stay in body due to mucoadhesion.