Study of the Preparation of Amorphous Itraconazole Formulations

Schematic representation of the effect of excipients in the stability to recrystallize amorphous pure glassy itraconazole when redispersing it in water.


María P. Fernández-Ronco *†, Matteo Salvalaglio †‡, Johannes Kluge †, and Marco Mazzotti †

† ETH Zurich, Institute of Process Engineering, Sonneggstrasse 3, 8092 Zurich, Switzerland

‡ Facoltá di Informatica, Istituto di Scienze Computazionali, Universitá della Svizzera Italiana, 6900 Lugano, Switzerland

Cryst. Growth Des., Article ASAP - DOI: 10.1021/cg501892j - Publication Date (Web): April 13, 2015

Copyright © 2015 American Chemical Society

http://pubs.acs.org/doi/abs/10.1021/cg501892j